Description
Single-Use Bioprocessing Equipment Market Overview
The single-use bioprocessing equipment market was valued at approximately USD 32.52 billion in 2024, is projected to reach around USD 37.81 billion in 2025, and is expected to grow to approximately USD 146.84 billion by 2034, exhibiting a CAGR of about 16.27% from 2025 to 2034.
The global single-use bioprocessing equipment market is experiencing rapid growth, driven by factors such as the increasing demand for biopharmaceuticals, cost-effectiveness of single-use technologies, and streamlined production processes.
One of the key advantages of single-use bioprocessing equipment is its flexibility and scalability. Unlike traditional stainless steel systems that require extensive cleaning and validation processes between batches, single-use systems can be easily disposed of after use, eliminating the risk of cross-contamination and reducing downtime. This flexibility allows biopharmaceutical manufacturers to quickly adapt to changing market demands and optimize their production processes.
Additionally, single-use bioprocessing equipment offers significant cost savings compared to traditional stainless steel equipment. The initial investment in single-use systems is lower, as there is no need for expensive cleaning and sterilization procedures. Moreover, single-use technologies reduce operational costs by minimizing labor requirements and increasing facility utilization rates. Overall, single-use bioprocessing equipment provides a more cost-effective and efficient solution for biopharmaceutical manufacturing.
Another driving factor behind the growth of the single-use bioprocessing equipment market is the increasing focus on sustainability and environmental impact. Single-use systems generate less waste, consume fewer resources, and require less energy compared to traditional stainless steel systems. This trend towards sustainability aligns with the growing emphasis on corporate social responsibility and environmentally friendly practices in the biopharmaceutical industry.
Single-Use Bioprocessing Equipment Market Dynamics
Drivers
The increasing demand for biopharmaceutical products, coupled with the need for rapid and flexible manufacturing processes, is a key driver for the adoption of single-use bioprocessing equipment. These disposable systems allow for quick changeovers between production runs, enabling biopharmaceutical companies to meet fluctuating market demands effectively. Additionally, the reduced cleaning and validation requirements of single-use systems result in cost savings and improved efficiency.
Restraints
Despite their many benefits, single-use bioprocessing equipment also faces certain challenges that may hinder widespread adoption. One of the primary restraints is the perception of lower reliability and robustness compared to traditional stainless-steel systems. Biopharmaceutical companies must carefully evaluate the quality and integrity of single-use components to ensure product safety and efficacy. Furthermore, the initial investment cost of single-use bioprocessing equipment can be higher than that of traditional systems, which may deter some organizations from making the switch.
Challenges
One of the main challenges in the single-use bioprocessing equipment market is the lack of standardization and regulatory guidelines. As this technology continues to evolve, industry stakeholders must work together to establish clear standards for design, manufacturing, and validation of single-use systems. Addressing concerns related to extractables and leachables is also crucial to ensure the safety and compliance of biopharmaceutical products manufactured using single-use equipment.
Opportunities
The growing trend towards personalized medicine and the increasing focus on biologics are creating new opportunities for single-use bioprocessing equipment manufacturers. These disposable systems offer the flexibility to produce small batches of highly specific therapies, allowing biopharmaceutical companies to cater to niche markets and patient populations. Moreover, advancements in single-use technology, such as the development of novel materials and innovative design features, are opening up possibilities for further efficiency gains and process improvements.
List of Key Players
- Thermo Fisher Scientific
- Sartorius AG
- Merck KGaA
- Danaher Corporation (Cytiva)
- Pall Corporation
- Eppendorf AG
- Corning Incorporated
- Avantor, Inc.
- Saint-Gobain Life Sciences
- Parker Hannifin Corporation
- Entegris, Inc.
- Meissner Filtration Products
- Repligen Corporation
- PBS Biotech
- ABEC, Inc.
- Cellexus
- Kuhner Shaker
- Distek, Inc.
- Applikon Biotechnology (Getinge)
- GE Healthcare (Now Cytiva)
Recent Developments:
Thermo Fisher Scientific – April 2025
Launched new single-use bioreactor systems (HyPerforma™ DynaDrive 5,000L) to scale up continuous bioprocessing.
Sartorius – February 2025
Opened a new manufacturing facility in Puerto Rico to expand single-use systems production for biopharma clients.
Merck KGaA – March 2025
Announced €300 million investment in Molsheim, France to expand manufacturing of single-use filtration assemblies.
Pall Corporation (Danaher) – January 2025
Introduced Allegro™ Connect Systems with integrated automation for downstream single-use chromatography.
Single-Use Bioprocessing Equipment Market Segmentation
By Product Type
- Bioreactors (Single-Use Bioreactors)
- Mixers
- Bags (Media Bags, Bioreactor Bags, Freezing Bags)
- Tubing Assemblies
- Filters (Depth Filters, Tangential Flow Filters)
- Sampling Systems
- Connectors & Clamps
- Sensors (pH, DO, Pressure)
- Manifolds and Storage Containers
By Application
- Cell Culture & Fermentation
- Filtration & Purification
- Mixing & Storage
- Aseptic Filling & Transfer
- Buffer & Media Preparation
By End User
- Biopharmaceutical Companies
- Contract Research Organizations (CROs)
- Contract Development & Manufacturing Organizations (CDMOs)
- Academic & Research Institutes
By Bioprocessing Stage
- Upstream Bioprocessing
- Downstream Bioprocessing
- Fill-Finish Operations
By Material
- Plastic (PE, PP, EVA)
- Silicone
- Other Polymer Films
Regional Market Insights: A Breakdown by Region
North America
Market Size: North America dominates the single-use bioprocessing equipment market, driven by the presence of a well-established biotech industry and increasing investment in biopharmaceutical R&D.
Key Players: Companies such as Thermo Fisher Scientific, Merck KGaA, and Danaher Corporation are leading the market with innovative single-use bioprocessing solutions.
Trends: The adoption of single-use bioprocessing equipment is on the rise in North America, driven by the need for cost-effective and flexible manufacturing solutions.
Europe
Market Growth: Europe is a key market for single-use bioprocessing equipment, with countries like Germany, France, and the UK leading the way in biopharmaceutical manufacturing.
Regulatory Environment: Stringent regulations and guidelines in Europe have encouraged the adoption of single-use bioprocessing equipment to ensure product safety and compliance.
Opportunities: The increasing demand for personalized medicine and biologics in Europe presents significant growth opportunities for single-use bioprocessing equipment manufacturers.
Asia Pacific
Emerging Market: The Asia Pacific region is witnessing rapid growth in the biotech industry, fueled by a growing population and rising healthcare expenditure.
Adoption Trends: Many biopharmaceutical companies in countries like China, Japan, and India are transitioning to single-use bioprocessing equipment to enhance efficiency and productivity.
Investment Opportunities: The increasing investment in biopharmaceutical research and development in Asia Pacific is driving the demand for advanced single-use bioprocessing solutions.
Target Audience
Biopharmaceutical & Biotechnology Companies
Contract Manufacturing Organizations (CMOs & CDMOs)
Academic & Government Research Institutes
Regulatory Authorities (e.g., FDA, EMA)
Equipment and Component Suppliers
Venture Capital Firms in Life Sciences
CROs involved in process development
Bioprocess Engineering Consultants
Hospital-based Biomanufacturing Units
Process Validation and QA/QC Teams
