Neurostimulation Therapy for Chronic Pain Market Size, Share, Trends, and Forecast (2025–2034): In...

June 21, 2025

Neurostimulation Therapy for Chronic Pain Market Size, Share, Trends, and Forecast (2025–2034): Industry Growth Analysis by Device Type (Spinal Cord Stimulators, Peripheral Nerve Stimulators, Deep Brain Stimulation, Transcutaneous Electrical Nerve Stimulation, Vagus Nerve Stimulation), Technology (Rechargeable, Non-rechargeable, Closed-loop, AI-powered Systems), Application (Neuropathic Pain, Musculoskeletal Pain, Cancer-related Pain, Post-surgical Pain, Headache/Migraine), End User (Hospitals & Pain Clinics, Ambulatory Surgery Centers, Home Care Settings, Physical Therapy Centers), Regional Insights, Competitive Landscape, and Market Opportunities

Description

Neurostimulation Therapy for Chronic Pain Market Overview

The Neurostimulation Therapy for Chronic Pain Market, specifically within the broader Neurostimulation Devices Market, is expected to grow from approximately USD 7.19 billion in 2024 and USD 8.1 billion in 2025 to around USD 23.24 billion by 2034, at a Compound Annual Growth Rate (CAGR) of 12.84% from 2025 to 2034.

The market for neurostimulation therapy for chronic pain is rapidly expanding, with a growing number of individuals turning to this innovative approach for relief. According to market research reports, the global neurostimulation devices market is expected to reach over $10 billion by 2025, highlighting the increasing demand for these advanced pain management solutions. This growth is driven by a variety of factors, including the rising prevalence of chronic pain conditions such as neuropathy, arthritis, and fibromyalgia.

Furthermore, advancements in technology have led to the development of more sophisticated neurostimulation devices that offer greater precision and customization for patients. This includes rechargeable devices that provide longer-lasting relief, wireless technologies that enhance convenience and mobility, and adjustable settings that allow for personalized treatment plans. As a result, neurostimulation therapy has become an attractive option for individuals seeking alternative pain management strategies.

The effectiveness of neurostimulation therapy for chronic pain has been well-documented in clinical studies and real-world applications. Research has shown that neurostimulation can provide significant pain relief for individuals with various chronic conditions, improving their quality of life and reducing their reliance on medications. In addition, many patients report a decrease in overall pain intensity, as well as improvements in physical function and mood.

Key considerations for individuals considering neurostimulation therapy include the cost of the treatment, insurance coverage, and the potential risks and side effects associated with the procedure. While neurostimulation therapy is generally considered safe and well-tolerated, some individuals may experience mild discomfort or skin irritation at the site of the device. It is essential for patients to discuss these factors with their healthcare provider and weigh the benefits and risks before proceeding with treatment.

Neurostimulation Therapy for Chronic Pain Market Dynamics

Drivers:

Neurostimulation therapy has gained traction in the medical field due to its effectiveness in managing chronic pain conditions. Patients who have not responded well to other treatment modalities are increasingly turning to neurostimulation as a viable option for pain relief. The advancement of technology has also played a significant role in the development of more sophisticated neurostimulation devices, making them more accessible to patients.

Restraints:

One of the main challenges facing neurostimulation therapy is the high cost of treatment. Insurance coverage for neurostimulation devices may vary, making it difficult for some patients to afford this type of therapy. Additionally, not all patients may be suitable candidates for neurostimulation, limiting the potential market for this treatment modality.

Challenges

Implementing neurostimulation therapy for chronic pain can present challenges in terms of the selection of the appropriate device and programming settings. Healthcare providers must undergo specialized training to ensure optimal patient outcomes with neurostimulation therapy. Moreover, managing patient expectations and educating them about the potential benefits and risks of neurostimulation can be a challenge.

Opportunities

Despite the challenges, there are several opportunities for the growth of neurostimulation therapy in the management of chronic pain. Continued research and development in the field of neurostimulation technology may lead to the introduction of more advanced and effective devices. Additionally, expanding insurance coverage for neurostimulation therapy can increase access to this treatment for patients in need.

Neurostimulation therapy is a promising option for individuals suffering from chronic pain. By targeting the nervous system to interrupt pain signals, neurostimulation can provide significant relief for patients who have not responded well to traditional pain management strategies. If you or a loved one is struggling with chronic pain, consider discussing neurostimulation therapy with your healthcare provider to explore this innovative treatment option.

List of Key Players

  1. Medtronic
  2. Abbott Laboratories
  3. Boston Scientific
  4. Nevro Corporation
  5. Stimwave LLC
  6. NeuroMetrix Inc.
  7. LivaNova PLC
  8. Nalu Medical
  9. Elekta (formerly Synapse Biomedical)
  10. NeuroPace (DBS)
  11. Curonix LLC
  12. Nervonik Inc.
  13. Abbott (Proclaim DRG)
  14. Biotronik
  15. Saluda Medical
  16. Axonics
  17. Bioness
  18. Aleva Neurotherapeutics
  19. Stryker
  20. Globus Medical

Recent Developments:

Curonix LLC – March 27, 2025
Launched NervPulse™ Therapy, an advanced nerve-specific PNS platform enhancing peripheral nerve stimulation with evidence-based programming for 26 nerves.

Nalu Medical – May 2025
Received FDA clearance for expanded MRI-conditional labeling of its PNS System, enabling patients with chronic pain to undergo whole-body MRI safely.

Nervonik Inc. – March 4, 2025
Raised $13 M Series A to advance its wireless, opioid-free PNS system in clinical development for chronic pain relief.

Medtronic – April 2024
Launched Inceptiv, the U.S.’s first closed-loop spinal cord stimulation system, dynamically adjusting stimulation based on physiologic feedback.

Neurostimulation Therapy for Chronic Pain Market Segmentation

By Device Type

  • Spinal Cord Stimulators (SCS)
  • Peripheral Nerve Stimulators (PNS)
  • Deep Brain Stimulation (DBS)
  • Transcutaneous Electrical Nerve Stimulation (TENS)
  • Vagus Nerve Stimulation (VNS)

By Technology

  • Rechargeable
  • Non-rechargeable
  • Closed-loop / Adaptive
  • AI-powered systems

By Application

  • Neuropathic pain
  • Musculoskeletal pain
  • Cancer-related pain
  • Post-surgical pain
  • Headache/migraine

By End User

  • Hospitals & Pain Clinics
  • Ambulatory Surgery Centers
  • Home Care Settings
  • Physical Therapy Centers

Regional Market Insights: A Breakdown by Region

North America

In North America, neurostimulation therapy for chronic pain has gained significant traction in recent years. The advanced healthcare infrastructure and high prevalence of chronic pain conditions have contributed to the growing adoption of this treatment modality. Leading market players are investing heavily in research and development to enhance the efficacy and accessibility of neurostimulation devices in this region.

Europe

Europe has also witnessed a surge in the utilization of neurostimulation therapy for chronic pain management. The increasing geriatric population and rising awareness about the benefits of non-pharmacological pain management strategies have propelled the market growth in this region. Regulatory bodies are actively involved in promoting the use of neurostimulation devices, further fueling market expansion.

Asia Pacific

The Asia Pacific region is emerging as a promising market for neurostimulation therapy, driven by the rising prevalence of chronic pain disorders and improving healthcare infrastructure. Countries like China and India are witnessing rapid adoption of innovative medical technologies, including neurostimulation devices. Market players are tapping into this lucrative market opportunity by launching localized products and expanding their distribution networks.

Latin America

Latin America is also experiencing a gradual shift towards non-invasive pain management solutions, with neurostimulation therapy gaining traction among healthcare professionals and patients alike. The region’s diverse patient population and increasing healthcare expenditure are creating favorable conditions for market growth. Leading manufacturers are focusing on establishing strategic partnerships and collaborations to strengthen their market presence in Latin America.

Middle East and Africa

In the Middle East and Africa region, there is a growing demand for advanced pain management solutions, including neurostimulation therapy. The increasing prevalence of chronic pain conditions, coupled with the region’s expanding healthcare sector, is driving market growth. Key market players are investing in expanding their product portfolios and enhancing the affordability of neurostimulation devices to cater to the diverse needs of patients in this region.

Target Audience

Pain Management Clinics & Hospitals

Anesthesiologists & Pain Specialists

Neurologists

Physical & Rehabilitation Centers

Ambulatory Surgery Centers

Home Healthcare Providers

Medical Device Distributors

Payers & Reimbursement Authorities

Investors & Strategic Partners

Regulatory Agencies

Neurostimulation Therapy for Chronic Pain Market Overview

The Neurostimulation Therapy for Chronic Pain Market, specifically within the broader Neurostimulation Devices Market, is expected to grow from approximately USD 7.19 billion in 2024 and USD 8.1 billion in 2025 to around USD 23.24 billion by 2034, at a Compound Annual Growth Rate (CAGR) of 12.84% from 2025 to 2034.

The market for neurostimulation therapy for chronic pain is rapidly expanding, with a growing number of individuals turning to this innovative approach for relief. According to market research reports, the global neurostimulation devices market is expected to reach over $10 billion by 2025, highlighting the increasing demand for these advanced pain management solutions. This growth is driven by a variety of factors, including the rising prevalence of chronic pain conditions such as neuropathy, arthritis, and fibromyalgia.

Furthermore, advancements in technology have led to the development of more sophisticated neurostimulation devices that offer greater precision and customization for patients. This includes rechargeable devices that provide longer-lasting relief, wireless technologies that enhance convenience and mobility, and adjustable settings that allow for personalized treatment plans. As a result, neurostimulation therapy has become an attractive option for individuals seeking alternative pain management strategies.

The effectiveness of neurostimulation therapy for chronic pain has been well-documented in clinical studies and real-world applications. Research has shown that neurostimulation can provide significant pain relief for individuals with various chronic conditions, improving their quality of life and reducing their reliance on medications. In addition, many patients report a decrease in overall pain intensity, as well as improvements in physical function and mood.

Key considerations for individuals considering neurostimulation therapy include the cost of the treatment, insurance coverage, and the potential risks and side effects associated with the procedure. While neurostimulation therapy is generally considered safe and well-tolerated, some individuals may experience mild discomfort or skin irritation at the site of the device. It is essential for patients to discuss these factors with their healthcare provider and weigh the benefits and risks before proceeding with treatment.

Neurostimulation Therapy for Chronic Pain Market Dynamics

Drivers:

Neurostimulation therapy has gained traction in the medical field due to its effectiveness in managing chronic pain conditions. Patients who have not responded well to other treatment modalities are increasingly turning to neurostimulation as a viable option for pain relief. The advancement of technology has also played a significant role in the development of more sophisticated neurostimulation devices, making them more accessible to patients.

Restraints:

One of the main challenges facing neurostimulation therapy is the high cost of treatment. Insurance coverage for neurostimulation devices may vary, making it difficult for some patients to afford this type of therapy. Additionally, not all patients may be suitable candidates for neurostimulation, limiting the potential market for this treatment modality.

Challenges

Implementing neurostimulation therapy for chronic pain can present challenges in terms of the selection of the appropriate device and programming settings. Healthcare providers must undergo specialized training to ensure optimal patient outcomes with neurostimulation therapy. Moreover, managing patient expectations and educating them about the potential benefits and risks of neurostimulation can be a challenge.

Opportunities

Despite the challenges, there are several opportunities for the growth of neurostimulation therapy in the management of chronic pain. Continued research and development in the field of neurostimulation technology may lead to the introduction of more advanced and effective devices. Additionally, expanding insurance coverage for neurostimulation therapy can increase access to this treatment for patients in need.

Neurostimulation therapy is a promising option for individuals suffering from chronic pain. By targeting the nervous system to interrupt pain signals, neurostimulation can provide significant relief for patients who have not responded well to traditional pain management strategies. If you or a loved one is struggling with chronic pain, consider discussing neurostimulation therapy with your healthcare provider to explore this innovative treatment option.

List of Key Players

  1. Medtronic
  2. Abbott Laboratories
  3. Boston Scientific
  4. Nevro Corporation
  5. Stimwave LLC
  6. NeuroMetrix Inc.
  7. LivaNova PLC
  8. Nalu Medical
  9. Elekta (formerly Synapse Biomedical)
  10. NeuroPace (DBS)
  11. Curonix LLC
  12. Nervonik Inc.
  13. Abbott (Proclaim DRG)
  14. Biotronik
  15. Saluda Medical
  16. Axonics
  17. Bioness
  18. Aleva Neurotherapeutics
  19. Stryker
  20. Globus Medical

Recent Developments:

Curonix LLC – March 27, 2025
Launched NervPulse™ Therapy, an advanced nerve-specific PNS platform enhancing peripheral nerve stimulation with evidence-based programming for 26 nerves.

Nalu Medical – May 2025
Received FDA clearance for expanded MRI-conditional labeling of its PNS System, enabling patients with chronic pain to undergo whole-body MRI safely.

Nervonik Inc. – March 4, 2025
Raised $13 M Series A to advance its wireless, opioid-free PNS system in clinical development for chronic pain relief.

Medtronic – April 2024
Launched Inceptiv, the U.S.’s first closed-loop spinal cord stimulation system, dynamically adjusting stimulation based on physiologic feedback.

Neurostimulation Therapy for Chronic Pain Market Segmentation

By Device Type

  • Spinal Cord Stimulators (SCS)
  • Peripheral Nerve Stimulators (PNS)
  • Deep Brain Stimulation (DBS)
  • Transcutaneous Electrical Nerve Stimulation (TENS)
  • Vagus Nerve Stimulation (VNS)

By Technology

  • Rechargeable
  • Non-rechargeable
  • Closed-loop / Adaptive
  • AI-powered systems

By Application

  • Neuropathic pain
  • Musculoskeletal pain
  • Cancer-related pain
  • Post-surgical pain
  • Headache/migraine

By End User

  • Hospitals & Pain Clinics
  • Ambulatory Surgery Centers
  • Home Care Settings
  • Physical Therapy Centers

Regional Market Insights: A Breakdown by Region

North America

In North America, neurostimulation therapy for chronic pain has gained significant traction in recent years. The advanced healthcare infrastructure and high prevalence of chronic pain conditions have contributed to the growing adoption of this treatment modality. Leading market players are investing heavily in research and development to enhance the efficacy and accessibility of neurostimulation devices in this region.

Europe

Europe has also witnessed a surge in the utilization of neurostimulation therapy for chronic pain management. The increasing geriatric population and rising awareness about the benefits of non-pharmacological pain management strategies have propelled the market growth in this region. Regulatory bodies are actively involved in promoting the use of neurostimulation devices, further fueling market expansion.

Asia Pacific

The Asia Pacific region is emerging as a promising market for neurostimulation therapy, driven by the rising prevalence of chronic pain disorders and improving healthcare infrastructure. Countries like China and India are witnessing rapid adoption of innovative medical technologies, including neurostimulation devices. Market players are tapping into this lucrative market opportunity by launching localized products and expanding their distribution networks.

Latin America

Latin America is also experiencing a gradual shift towards non-invasive pain management solutions, with neurostimulation therapy gaining traction among healthcare professionals and patients alike. The region’s diverse patient population and increasing healthcare expenditure are creating favorable conditions for market growth. Leading manufacturers are focusing on establishing strategic partnerships and collaborations to strengthen their market presence in Latin America.

Middle East and Africa

In the Middle East and Africa region, there is a growing demand for advanced pain management solutions, including neurostimulation therapy. The increasing prevalence of chronic pain conditions, coupled with the region’s expanding healthcare sector, is driving market growth. Key market players are investing in expanding their product portfolios and enhancing the affordability of neurostimulation devices to cater to the diverse needs of patients in this region.

Target Audience

Pain Management Clinics & Hospitals

Anesthesiologists & Pain Specialists

Neurologists

Physical & Rehabilitation Centers

Ambulatory Surgery Centers

Home Healthcare Providers

Medical Device Distributors

Payers & Reimbursement Authorities

Investors & Strategic Partners

Regulatory Agencies

Table Of Contents:

Executive Summary
1.1. Market Overview
1.2. Key Findings
1.3. Market Size and Growth Forecast (2025–2035)
1.4. Key Market Trends and Drivers
1.5. Challenges and Restraints
1.6. Market Opportunities
Introduction
2.1. Definition and Scope
2.2. Research Methodology
 2.2.1. Data Collection Approach
 2.2.2. Market Estimation and Forecasting Techniques
 2.2.3. Assumptions and Limitations
2.3. Industry Stakeholders
Market Dynamics
3.1. Market Drivers
 3.1.1. Rising Prevalence of Chronic Pain Conditions
 3.1.2. Growing Use of Minimally Invasive Technologies
 3.1.3. Technological Advancements in Neurostimulation
 3.1.4. Reimbursement Coverage Expansion
3.2. Market Restraints
 3.2.1. High Device and Procedure Costs
 3.2.2. Limited Reimbursement in Certain Regions
 3.2.3. Physician Training and Adoption Barriers
3.3. Market Opportunities
 3.3.1. Emerging Closed-Loop and Adaptive Systems
 3.3.2. Expanding Applications in Peripheral Nerve and Migraine Pain
 3.3.3. Rising Home-based and Wearable Therapies
3.4. Market Challenges
 3.4.1. Regulatory Approval Complexity
 3.4.2. Competition from Pharmacological Alternatives
 3.4.3. Long-term Efficacy Data Gaps
Neurostimulation Therapy Market Size and Forecast (2025–2035)
4.1. Global Market Size and CAGR Analysis
4.2. Regional Market Size and Growth Trends
 4.2.1. North America
 4.2.2. Europe
 4.2.3. Asia-Pacific
 4.2.4. South America
 4.2.5. Middle East and Africa
Market Segmentation by Device Type
5.1. Spinal Cord Stimulation (SCS)
5.2. Peripheral Nerve Stimulation (PNS)
5.3. Deep Brain Stimulation (DBS)
5.4. Vagus Nerve Stimulation (VNS)
5.5. Transcutaneous Electrical Nerve Stimulation (TENS)
Market Segmentation by Technology
6.1. Rechargeable Systems
6.2. Non-rechargeable Systems
6.3. Closed-loop / Adaptive Systems
6.4. Wireless and Wearable Systems
Market Segmentation by Application
7.1. Neuropathic Pain
7.2. Musculoskeletal Pain
7.3. Cancer-Related Pain
7.4. Post-Surgical Pain
7.5. Migraine and Headache Disorders
Market Segmentation by End User
8.1. Hospitals and Pain Management Clinics
8.2. Ambulatory Surgical Centers
8.3. Home Care Settings
8.4. Rehabilitation and Physical Therapy Centers
Technological Advancements in Neurostimulation
9.1. Closed-Loop and ECAP-Controlled Systems
9.2. AI and Machine Learning in Device Programming
9.3. Minimally Invasive Implantation Techniques
9.4. Integration with Mobile Health and Telemedicine
Regional Analysis and Growth Projections
10.1. North America
 10.1.1. United States
 10.1.2. Canada
10.2. Europe
 10.2.1. Germany
 10.2.2. France
 10.2.3. United Kingdom
 10.2.4. Italy
10.3. Asia-Pacific
 10.3.1. China
 10.3.2. Japan
 10.3.3. South Korea
 10.3.4. India
10.4. South America
 10.4.1. Brazil
 10.4.2. Argentina
10.5. Middle East and Africa
 10.5.1. UAE
 10.5.2. Saudi Arabia
 10.5.3. South Africa
Competitive Landscape
11.1. Market Share Analysis of Key Players
11.2. Competitive Strategies and Recent Developments
11.3. Company Profiles
 11.3.1. Medtronic
 11.3.2. Abbott Laboratories
 11.3.3. Boston Scientific
 11.3.4. Nevro Corporation
 11.3.5. Stimwave LLC
 11.3.6. Saluda Medical
 11.3.7. Nalu Medical
 11.3.8. LivaNova PLC
 11.3.9. NeuroMetrix, Inc.
 11.3.10. NeuroPace
Investment and Expansion Strategies
12.1. Mergers and Acquisitions
12.2. Strategic Partnerships and Collaborations
12.3. R&D Investments and Clinical Trials
12.4. Product Launches and Market Expansion
Frequently Asked Question(FAQ):
Q1. How big is the Neurostimulation Therapy for Chronic Pain Market?
Q2. What is the Neurostimulation Therapy for Chronic Pain Market growth?
Q3. Which segment accounted for the largest Neurostimulation Therapy for Chronic Pain Market share?
Q4. What is the Neurostimulation Therapy for Chronic Pain Market CAGR?
Q5. What factors are driving the growth of this market?
Q6. What challenges does the Neurostimulation Therapy for Chronic Pain Market face?
Q7. What is the forecasted growth rate (CAGR) for this market?
Q8. Who are the leading players in the Neurostimulation Therapy for Chronic Pain Market?

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