Liquid Biopsy for Cancer Treatment Market Size, Share, and Forecast (2025–2034): Industry Analysis...

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Liquid Biopsy for Cancer Treatment Market Size, Share, and Forecast (2025–2034): Industry Analysis by Biomarker Type, Application, Technology Type, End User, Regional Insights, Competitive Landscape, and Growth Opportunities

Description

Liquid Biopsy for Cancer Treatment Market Overview

The global liquid biopsy for cancer treatment market was valued at approximately USD 6.18 billion in 2024 and is projected to reach around USD 7.05 billion in 2025, and USD 23.94 billion by 2034, growing at a CAGR of about 14.5% from 2025 to 2034.

The global liquid biopsy market is experiencing rapid growth, driven by the increasing prevalence of cancer worldwide and the growing demand for personalized medicine. According to recent studies, the market is expected to reach $3.4 billion by 2023, with a compound annual growth rate (CAGR) of 23.4%. Liquid biopsy tests are becoming increasingly popular among oncologists and patients due to their numerous advantages over traditional tissue biopsy, such as minimal invasiveness, real-time monitoring, and the ability to capture tumor heterogeneity.

Liquid biopsy tests have shown great potential in the early detection of cancer, as they can detect circulating tumor DNA even before symptoms appear. This early detection allows for timely intervention and improved patient outcomes. Additionally, liquid biopsy can be used to monitor treatment response and detect minimal residual disease, enabling oncologists to adjust therapy regimens accordingly. Moreover, liquid biopsy can help identify resistance mutations, guiding the selection of targeted therapies and improving treatment efficacy.

The liquid biopsy market is highly competitive, with several key players dominating the industry. Companies such as Guardant Health, GRAIL, and Foundation Medicine are at the forefront of liquid biopsy technology, offering a wide range of tests for various cancer types. These companies are constantly innovating and investing in research and development to improve the sensitivity and accuracy of liquid biopsy tests. As the market continues to grow, new players are entering the space, driving further innovation and competition.

Liquid biopsy is set to revolutionize cancer treatment by providing oncologists with valuable information about the genetic makeup of tumors and guiding personalized treatment decisions. With its ability to detect cancer early, monitor treatment response, and identify resistance mutations, liquid biopsy is transforming the way we approach cancer care. As the global liquid biopsy market continues to expand, we can expect to see even more advanced and sensitive tests that will further improve patient outcomes and revolutionize oncology as we know it.

Liquid Biopsy for Cancer Treatment Market Dynamics

Drivers

Liquid biopsy offers a non-invasive method for detecting cancer-related biomarkers, making it easier for patients to undergo regular monitoring without the need for invasive procedures.

Liquid biopsy can provide real-time information on the molecular profile of the tumor, allowing for more personalized and targeted treatment options.

Liquid biopsy has the potential to detect cancer at an early stage, increasing the chances of successful treatment and improving patient outcomes.

Restraints

The cost of liquid biopsy procedures can be prohibitive for some patients, limiting access to this cutting-edge technology.

False-positive results can occur with liquid biopsy, leading to unnecessary anxiety and stress for patients.

Liquid biopsy is still a relatively new technology, and more research is needed to fully understand its limitations and potential complications.

Challenges

Standardization of liquid biopsy procedures and analysis methods is needed to ensure consistent and reliable results across different laboratories.

Education and awareness are key challenges in the adoption of liquid biopsy, as both patients and healthcare providers may be hesitant to embrace this new technology.

Regulatory approvals and insurance coverage for liquid biopsy procedures can vary, creating barriers to widespread adoption.

Opportunities

Liquid biopsy has the potential to revolutionize cancer treatment by enabling early detection, personalized medicine, and targeted therapy.

Continued research and development in liquid biopsy technology can lead to improvements in accuracy, sensitivity, and cost-effectiveness.

Collaboration between industry stakeholders, researchers, and regulatory bodies can help drive innovation and facilitate the integration of liquid biopsy into standard clinical practice.

List of Key Players

  1. Guardant Health
  2. Natera
  3. Roche Diagnostics
  4. Illumina
  5. Thermo Fisher Scientific
  6. QIAGEN
  7. Myriad Genetics
  8. Bio-Rad Laboratories
  9. Agilent Technologies
  10. Foundation Medicine (Roche)
  11. Genomic Health
  12. Exact Sciences
  13. Labcorp
  14. Biocept
  15. Menarini Silicon Biosystems
  16. Inivata
  17. CIRCULOGENE
  18. Sophia Genetics
  19. Hedera Dx
  20. Guardant360 CDx (Guardant)

Recent Developments:

Guardant Health – May 27, 2025
Introduced nearly a dozen new “smart” liquid biopsy applications for Guardant360, including multi-marker tumor phenotyping and enhanced treatment guidance insights.

Labcorp – April 2025
Launched “Plasma Detect”: the first tumor-informed liquid biopsy MRD test for recurrence risk stratification in cancer patients.

Hedera Dx – May 29, 2025
Announced the launch of a 42-gene liquid biopsy panel to guide precision cancer therapies, expanding diagnostic offerings.

Liquid Biopsy for Cancer Treatment Market Segmentation

By Biomarker Type

  • Circulating Tumor DNA (ctDNA)
  • Circulating Tumor Cells (CTCs)
  • Exosomes & Extracellular Vesicles
  • Circulating RNA (miRNA, mRNA)
  • Protein-based Biomarkers

By Application

  • Early Cancer Detection & Screening
  • Treatment Selection & Therapy Guidance
  • Minimal Residual Disease (MRD) Monitoring & Recurrence
  • Treatment Response & Progression Monitoring

By Technology Type

  • PCR-based assays (e.g., digital PCR)
  • Next-Generation Sequencing (NGS) panels
  • Microarray & Mass Spectrometry assays
  • Bioinformatics & AI-integrated analysis

By End User

  • Reference Laboratories
  • Hospital-Based Laboratories
  • Academic & Research Institutions
  • Diagnostic Service Providers

Regional Market Insights: A Breakdown by Region

North America

In North America, the adoption of liquid biopsies for cancer treatment has been rapid. With a strong emphasis on technological innovation and a high prevalence of cancer cases, this region has been quick to embrace this cutting-edge technology. Major players in the healthcare industry are investing heavily in research and development, driving the market forward.

Europe

Europe has also seen significant growth in the use of liquid biopsies for cancer treatment. Countries such as the United Kingdom, Germany, and France have been at the forefront of this technology, with healthcare systems that prioritize innovation and patient care. The market is expected to continue expanding as more hospitals and clinics integrate liquid biopsies into their standard practices.

Asia Pacific

In the Asia Pacific region, the adoption of liquid biopsies for cancer treatment is steadily increasing. Countries like China, Japan, and South Korea are investing in research and development to improve cancer diagnostics and treatment options. As healthcare infrastructure continues to improve, more patients in this region will have access to this cutting-edge technology.

Latin America

Latin America is also seeing growth in the use of liquid biopsies for cancer treatment. Countries like Brazil, Mexico, and Argentina are investing in healthcare technology to improve patient outcomes and reduce healthcare costs. As the market continues to mature, more patients in Latin America will benefit from the advances in cancer diagnostics and personalized treatment options.

Middle East and Africa

In the Middle East and Africa, the adoption of liquid biopsies for cancer treatment is still in the early stages. However, as healthcare systems in this region continue to develop and access to medical technology improves, the use of liquid biopsies is expected to increase. This technology has the potential to revolutionize cancer care in underserved areas, providing patients with more accurate diagnoses and personalized treatment plans.

Target Audience

Hospitals, Oncology Clinics, and Pathology Labs

Reference & Diagnostic Laboratories

Biopharma & Precision Medicine Developers

Contract Research Organizations (CROs)

Genomic & Molecular Testing Providers

Regulatory & Health Authorities

Payers & Health Insurance Providers

Research Institutions & Academic Centers

Investors & Strategic Healthcare Partners

Patient Advocacy Groups focused on early detection

Liquid Biopsy for Cancer Treatment Market Overview

The global liquid biopsy for cancer treatment market was valued at approximately USD 6.18 billion in 2024 and is projected to reach around USD 7.05 billion in 2025, and USD 23.94 billion by 2034, growing at a CAGR of about 14.5% from 2025 to 2034.

The global liquid biopsy market is experiencing rapid growth, driven by the increasing prevalence of cancer worldwide and the growing demand for personalized medicine. According to recent studies, the market is expected to reach $3.4 billion by 2023, with a compound annual growth rate (CAGR) of 23.4%. Liquid biopsy tests are becoming increasingly popular among oncologists and patients due to their numerous advantages over traditional tissue biopsy, such as minimal invasiveness, real-time monitoring, and the ability to capture tumor heterogeneity.

Liquid biopsy tests have shown great potential in the early detection of cancer, as they can detect circulating tumor DNA even before symptoms appear. This early detection allows for timely intervention and improved patient outcomes. Additionally, liquid biopsy can be used to monitor treatment response and detect minimal residual disease, enabling oncologists to adjust therapy regimens accordingly. Moreover, liquid biopsy can help identify resistance mutations, guiding the selection of targeted therapies and improving treatment efficacy.

The liquid biopsy market is highly competitive, with several key players dominating the industry. Companies such as Guardant Health, GRAIL, and Foundation Medicine are at the forefront of liquid biopsy technology, offering a wide range of tests for various cancer types. These companies are constantly innovating and investing in research and development to improve the sensitivity and accuracy of liquid biopsy tests. As the market continues to grow, new players are entering the space, driving further innovation and competition.

Liquid biopsy is set to revolutionize cancer treatment by providing oncologists with valuable information about the genetic makeup of tumors and guiding personalized treatment decisions. With its ability to detect cancer early, monitor treatment response, and identify resistance mutations, liquid biopsy is transforming the way we approach cancer care. As the global liquid biopsy market continues to expand, we can expect to see even more advanced and sensitive tests that will further improve patient outcomes and revolutionize oncology as we know it.

Liquid Biopsy for Cancer Treatment Market Dynamics

Drivers

Liquid biopsy offers a non-invasive method for detecting cancer-related biomarkers, making it easier for patients to undergo regular monitoring without the need for invasive procedures.

Liquid biopsy can provide real-time information on the molecular profile of the tumor, allowing for more personalized and targeted treatment options.

Liquid biopsy has the potential to detect cancer at an early stage, increasing the chances of successful treatment and improving patient outcomes.

Restraints

The cost of liquid biopsy procedures can be prohibitive for some patients, limiting access to this cutting-edge technology.

False-positive results can occur with liquid biopsy, leading to unnecessary anxiety and stress for patients.

Liquid biopsy is still a relatively new technology, and more research is needed to fully understand its limitations and potential complications.

Challenges

Standardization of liquid biopsy procedures and analysis methods is needed to ensure consistent and reliable results across different laboratories.

Education and awareness are key challenges in the adoption of liquid biopsy, as both patients and healthcare providers may be hesitant to embrace this new technology.

Regulatory approvals and insurance coverage for liquid biopsy procedures can vary, creating barriers to widespread adoption.

Opportunities

Liquid biopsy has the potential to revolutionize cancer treatment by enabling early detection, personalized medicine, and targeted therapy.

Continued research and development in liquid biopsy technology can lead to improvements in accuracy, sensitivity, and cost-effectiveness.

Collaboration between industry stakeholders, researchers, and regulatory bodies can help drive innovation and facilitate the integration of liquid biopsy into standard clinical practice.

List of Key Players

  1. Guardant Health
  2. Natera
  3. Roche Diagnostics
  4. Illumina
  5. Thermo Fisher Scientific
  6. QIAGEN
  7. Myriad Genetics
  8. Bio-Rad Laboratories
  9. Agilent Technologies
  10. Foundation Medicine (Roche)
  11. Genomic Health
  12. Exact Sciences
  13. Labcorp
  14. Biocept
  15. Menarini Silicon Biosystems
  16. Inivata
  17. CIRCULOGENE
  18. Sophia Genetics
  19. Hedera Dx
  20. Guardant360 CDx (Guardant)

Recent Developments:

Guardant Health – May 27, 2025
Introduced nearly a dozen new “smart” liquid biopsy applications for Guardant360, including multi-marker tumor phenotyping and enhanced treatment guidance insights.

Labcorp – April 2025
Launched “Plasma Detect”: the first tumor-informed liquid biopsy MRD test for recurrence risk stratification in cancer patients.

Hedera Dx – May 29, 2025
Announced the launch of a 42-gene liquid biopsy panel to guide precision cancer therapies, expanding diagnostic offerings.

Liquid Biopsy for Cancer Treatment Market Segmentation

By Biomarker Type

  • Circulating Tumor DNA (ctDNA)
  • Circulating Tumor Cells (CTCs)
  • Exosomes & Extracellular Vesicles
  • Circulating RNA (miRNA, mRNA)
  • Protein-based Biomarkers

By Application

  • Early Cancer Detection & Screening
  • Treatment Selection & Therapy Guidance
  • Minimal Residual Disease (MRD) Monitoring & Recurrence
  • Treatment Response & Progression Monitoring

By Technology Type

  • PCR-based assays (e.g., digital PCR)
  • Next-Generation Sequencing (NGS) panels
  • Microarray & Mass Spectrometry assays
  • Bioinformatics & AI-integrated analysis

By End User

  • Reference Laboratories
  • Hospital-Based Laboratories
  • Academic & Research Institutions
  • Diagnostic Service Providers

Regional Market Insights: A Breakdown by Region

North America

In North America, the adoption of liquid biopsies for cancer treatment has been rapid. With a strong emphasis on technological innovation and a high prevalence of cancer cases, this region has been quick to embrace this cutting-edge technology. Major players in the healthcare industry are investing heavily in research and development, driving the market forward.

Europe

Europe has also seen significant growth in the use of liquid biopsies for cancer treatment. Countries such as the United Kingdom, Germany, and France have been at the forefront of this technology, with healthcare systems that prioritize innovation and patient care. The market is expected to continue expanding as more hospitals and clinics integrate liquid biopsies into their standard practices.

Asia Pacific

In the Asia Pacific region, the adoption of liquid biopsies for cancer treatment is steadily increasing. Countries like China, Japan, and South Korea are investing in research and development to improve cancer diagnostics and treatment options. As healthcare infrastructure continues to improve, more patients in this region will have access to this cutting-edge technology.

Latin America

Latin America is also seeing growth in the use of liquid biopsies for cancer treatment. Countries like Brazil, Mexico, and Argentina are investing in healthcare technology to improve patient outcomes and reduce healthcare costs. As the market continues to mature, more patients in Latin America will benefit from the advances in cancer diagnostics and personalized treatment options.

Middle East and Africa

In the Middle East and Africa, the adoption of liquid biopsies for cancer treatment is still in the early stages. However, as healthcare systems in this region continue to develop and access to medical technology improves, the use of liquid biopsies is expected to increase. This technology has the potential to revolutionize cancer care in underserved areas, providing patients with more accurate diagnoses and personalized treatment plans.

Target Audience

Hospitals, Oncology Clinics, and Pathology Labs

Reference & Diagnostic Laboratories

Biopharma & Precision Medicine Developers

Contract Research Organizations (CROs)

Genomic & Molecular Testing Providers

Regulatory & Health Authorities

Payers & Health Insurance Providers

Research Institutions & Academic Centers

Investors & Strategic Healthcare Partners

Patient Advocacy Groups focused on early detection

Table Of Contents:

1. Executive Summary
1.1. Market Overview
1.2. Key Findings
1.3. Market Size and Growth Forecast (2025–2034)
1.4. Key Market Trends and Drivers
1.5. Challenges and Restraints
1.6. Market Opportunities
2. Introduction
2.1. Definition and Scope
2.2. Research Methodology
 2.2.1. Data Collection Approach
 2.2.2. Market Estimation and Forecasting Techniques
 2.2.3. Assumptions and Limitations
2.3. Industry Stakeholders
3. Market Dynamics
3.1. Market Drivers
 3.1.1. Growing Demand for Non-Invasive Cancer Diagnostics
 3.1.2. Advancements in ctDNA and CTC Detection Technologies
 3.1.3. Integration of AI and Bioinformatics in Liquid Biopsy
3.2. Market Restraints
 3.2.1. High Costs of Advanced Liquid Biopsy Tests
 3.2.2. Limited Sensitivity for Early-Stage Cancer Detection
3.3. Market Opportunities
 3.3.1. Expansion in Early Cancer Screening Applications
 3.3.2. Rise in Companion Diagnostics for Targeted Therapy
3.4. Market Challenges
 3.4.1. Regulatory and Reimbursement Hurdles
 3.4.2. Technical Limitations in Biomarker Quantification
4. Liquid Biopsy Market Size and Forecast (2025–2034)
4.1. Global Market Size and CAGR Analysis
4.2. Regional Market Size and Growth Trends
 4.2.1. North America
 4.2.2. Europe
 4.2.3. Asia-Pacific
 4.2.4. South America
 4.2.5. Middle East & Africa
5. Market Segmentation by Biomarker Type
5.1. Circulating Tumor Cells (CTCs)
5.2. Circulating Tumor DNA (ctDNA)
5.3. Exosomes and Extracellular Vesicles
5.4. Circulating RNA (miRNA, mRNA)
5.5. Protein-Based Biomarkers
6. Market Segmentation by Technology
6.1. PCR-Based Assays
6.2. Next-Generation Sequencing (NGS)
6.3. Digital Droplet PCR (ddPCR)
6.4. Microarray-Based Tests
6.5. Bioinformatics & AI-Enhanced Platforms
7. Market Segmentation by Application
7.1. Early Cancer Detection
7.2. Therapy Selection and Companion Diagnostics
7.3. Treatment Monitoring
7.4. Minimal Residual Disease (MRD) Detection
7.5. Recurrence Prediction
8. Market Segmentation by End-User
8.1. Hospitals and Cancer Centers
8.2. Reference Laboratories
8.3. Academic and Research Institutions
8.4. Biopharmaceutical Companies
8.5. Diagnostic Laboratories
9. Market Segmentation by Cancer Type
9.1. Lung Cancer
9.2. Breast Cancer
9.3. Colorectal Cancer
9.4. Prostate Cancer
9.5. Others (Pancreatic, Ovarian, etc.)
10. Technological Advancements in Liquid Biopsy
10.1. AI-Driven Biomarker Analysis
10.2. Integration with Multi-Omics Data
10.3. Development of Point-of-Care Liquid Biopsy Kits
10.4. Novel Sampling and Preservation Techniques
10.5. Smart Monitoring with Digital Health Tools
11. Regional Analysis and Growth Projections
11.1. North America
 11.1.1. United States
 11.1.2. Canada
11.2. Europe
 11.2.1. Germany
 11.2.2. United Kingdom
 11.2.3. France
 11.2.4. Italy
11.3. Asia-Pacific
 11.3.1. China
 11.3.2. Japan
 11.3.3. South Korea
 11.3.4. India
11.4. South America
 11.4.1. Brazil
 11.4.2. Argentina
11.5. Middle East & Africa
 11.5.1. UAE
 11.5.2. Saudi Arabia
 11.5.3. South Africa
12. Competitive Landscape
12.1. Market Share Analysis of Key Players
12.2. Competitive Strategies and Recent Developments
12.3. Company Profiles
 12.3.1. Guardant Health
 12.3.2. Natera
 12.3.3. Roche
 12.3.4. Illumina
 12.3.5. Thermo Fisher Scientific
 12.3.6. QIAGEN
 12.3.7. Biocept
 12.3.8. Exact Sciences
 12.3.9. Inivata
 12.3.10. Freenome
 12.3.11. Epigene Labs
 12.3.12. Labcorp
13. Investment and Expansion Strategies
13.1. Mergers and Acquisitions
13.2. Collaborations and Strategic Alliances
13.3. Expansion in Emerging Markets
13.4. R&D Investments in Liquid Biopsy Technologies
13.5. Product Launches and Commercial Scale-Up

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